Knock out one gene and mice, cattle, whippets, and at least one documented human infant all put on twice the normal muscle mass. Myostatin inhibition is one of the most reproducible dramatic phenotypes in mammalian biology, which is exactly why it became a grey-market peptide category — follistatin and ACE-031 chief among them. What the animal data actually shows, why the one drug that matched it in a human trial got shut down by nosebleeds, and why "follistatin-344" in a vial is not the same intervention as the gene therapy that generated the exciting numbers.
Gene-Doping
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Follistatin, ACE-031, and the Myostatin Inhibitor Gene-Doping Frontier