In June 2026, Andrew Huberman spent nearly three hours with physician Abud Bakri walking through BPC-157, GHK-Cu, epithalon, pinealon, thymosin alpha-1, GLP-1s, and retatrutide. The episode is a genuinely useful map of what people are injecting and why. It is also a case study in how conversational time can flatten a very steep evidence gradient. A peptide-by-peptide fact-check of the claims, the mechanisms, and the regulatory maze in between.
Evidence-Based
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The Huberman Lab Peptides Episode, Reviewed: What Dr. Bakri Said and What Survives Scrutiny -
The Science of Muscle Hypertrophy: Tension, Volume, and the Folklore What actually makes a muscle grow, separated from the gym mythology. The mechanotransduction-to-mTOR pathway, mechanical tension versus the metabolic stress red herring, the volume and proximity-to-failure evidence, protein intake numbers that hold up, and an honest dose-response model you can train by.
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Diet and Cognition: What the Evidence Actually Supports, and What the Marketing Sells Most diet-and-cognition claims rest on observational studies that systematically over-promise, and the few large randomized trials that tested the headline diets came back muted. A skeptical-engineer walk through the Mediterranean and MIND data, omega-3s honestly, the supplement graveyard, and the one mechanism that actually holds up.